One needs to be well aware of the potential risks of any new form of therapy; cell transplantation has the potential for dangerous side effects. Specifically, newly introduced cells could conceivably form cardiac or metastatic tumors, disrupt the electrical rhythm of the heart, produce inappropriate chemical signals that adversely affect normal tissue or normal physiology, or evolve pathological stiffness or fragility, leading to mechanical failure of the heart. Moreover, aberrant cellular behavior or unseen intracellular lesions could unknowingly accumulate during the laboratory production of the therapeutic materials. Although these abnormalities might not be evident ex vivo, they could lead to unforeseen clinical problems in the patient. Therefore, extensive safety measures must be taken as cell transplantation therapies are further developed and more clinical trials are undertaken. Nevertheless, the potential benefits of cell transplantation therapies are exciting and will continue as a major area of intensive research in the near future.

Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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