Malignant Melanoma

Maihgan A. Kavanagh and Donald L. Morton

John Wayne Cancer Institute at Saint John's Health Center, Santa Monica, California, U.S.A.

Robert A. Weisman

Division of Otolaryngology, Head and Neck Oncology Program, Moores Cancer Center, University of California, San Diego, California, U.S.A.

■ Introduction 274

■ Epidemiology 274

■ Pathogenesis 274

■ Clinical Manifestations 274

■ Primary Lesion 274

■ Regional Metastasis 276

■ Systemic Disease 276

■ Diagnosis 276

■ Tissue Biopsy 278

■ Treatment 278

■ Loco-Regional Disease (Nodal Assessment) 278

■ Systemic Disease 280

■ Complications and Prognosis 281

■ Mucosal Melanomas—Special Considerations 281

■ References 283

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