FIGURE 13-19 Examples of antiestrogenic and antiprogestinal compounds. Each category of antagonist can be divided into class I (partial antagonist) or class II (pure antagonist).
TABLE 13-7 Proposed Steps in Steroid Hormone Action for Site of Action of Steroid Antagonists (Antihormones)
Transport through blood on serum protein Entry into target cell Receptor binding by Iigand
Competition with natural hormone Allosteric modification of natural hormone binding Generation of a new conformational form of the receptor Receptor-ligand actions
Interference with receptor dimer formation (either homo- or heterodimers)
Reduction or inhibition of transcription-activating function(s)
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Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.