Hormones And Inflammation

A. Introduction

The body's protection against infection, invading pathogens, or injury is a complex, overlapping network that includes the immune, inflammatory, and allergic systems. It is beyond the scope of this presentation to provide an in-depth discussion of these topics. What is presented is a brief overview that illustrates the extensive involvement of classical hormones, paracrine agents, lymphokines, cytokines, and growth factors generated by cells present in the circulatory system, which function in the inflammation and immune responses.

B. Inflammation Response

The acute inflammatory response comprises innate reactions (reactions not involving immunological components) that occur locally at the site of injury or infec-

TABLE 15-12 Biochemical Properties of Colony-Stimulating Factors"
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