Trkb Trkc

FIGURE 19-13 Neurotrophin-neurotrophin receptor interactions. Reproduced with permission from Maness, L. M., Kastin, A. J., Weber, J. T„ Banks, W. A., Beckman, B. S., and Zadina, J. E. (1994). The neurotrophins and their receptors: Structure, function, and neuropathology. Neurosci. Biobehav. Rev., 18, 143-159.

and binds NGF as well as NF-3 and BDNF. Binding of neurotrophic factors to trk receptors is summarized in Figure 19-13. Furthermore, the signal transduction pathway following interaction with the trk receptor involves several components, including PI3k, SRC, RAS, PLC-y-1, and downstream pathways. These are summarized in Figure 19-15. Thyroid hormone positively regulates the levels of NGF in the brain during development and is required for normal development.

Hematopoietic growth factors are discussed in Chapter 15. Other growth factors relating to the gastrointestinal tract are discussed in Chapter 8.

Cure Tennis Elbow Without Surgery

Cure Tennis Elbow Without Surgery

Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.

Get My Free Ebook

Post a comment