Release stimulated by
Possible mode of action
Hypothalamus (see Chapter 3) Pancreatic D cells (see Chapter 7)
Stomach, duodenum, colon
Pancreas: glucose, arginine Hypothalamus: inhibit growth hormone release GI tract: after ingestion of a mixed meal, but SS-28 8> SS-14 Hypothalamus: inhibit release of growth hormone Pancreas: inhibit insulin and glucagon secretion GI tract: paracrine agent to inhibit gastrin release and acid secretion Interaction with specific membrane receptors, coupled to Gs proteins and adenylate cylase; there is evidence for separate receptors for SS-28 and SS-14
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All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.