Oh

i chch2nhch(ch3)2

Pronethalol

Phentolamine

(ch2)2ci

,ch2nchch2oc6h6 I

Phenoxybenzamine

Ergotamine

FIGURE 11-2 (A) Compounds with epinephrine-like (pressor) activity. The numbers in parentheses represent the relative pressor activity (epinephrine = 1.0). Reproduced from Frieden, E. H. (1976). "Chemical Endocrinology," p. 46. Academic Press, New York. (B) Specific antagonists of ^-adrenergic receptors. (C) Specific antagonists of «-adrenergic receptors.

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