Nadph

NADP+

Ca2+

figure 6-8 Proposed mechanisms for production of H202.

(A) Superoxide anion, 02~, is first produced from 02 by the NADPH oxidase enzyme and then converted by dismutation, mediated by the enzyme superoxide dismutase (SOD), on the inside of the apical membrane (see Fig. 6-7); the H202 is then released to the outside.

(B) H202 is generated directly from 02 by the NADPH oxidase outside the cell. As indicated, changes in intracellular [Ca2+] have been shown to stimulate the production of H202. [Modified with permission from Gentile, F., DiLauro, R., and Salvatore, G. (1995). Biosynthesis and secretion of thyroid hormones. In "Endocrinology" (L. J. DeGroot et al, eds.), Vol. 1, Chapt. 34, pp. 517-542. W. B. Saunders, Philadelphia, PA.]

Cure Tennis Elbow Without Surgery

Cure Tennis Elbow Without Surgery

Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.

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