HRE3 A rCTT^T
FIGURE 10-25 HRR of the MMTV promoter. Schematic representation of the MMTV regulatory region, including the hormone regulatory region (HRR) with the receptor-binding sites (HRE 1-4), the palindromic binding site for CTF/NFI (NF-1), and the two octamer motifs (Octs) upstream of the TATA box (TFIID). The nucleotide sequence of the region between -187 and -37 is shown. Note the varied spacing of the half-palindromes in HRE1 and HRE2. Reproduced with permission from Truss, M., and Beato, M. (1993). Steroid hormone receptors: Interaction with deoxyribonucleic acid and transcription factors. Endocr. Rev. 14,459-479.
FIGURE 10-26 Model for the stabilization of the preinitiation complex by an RXR-RAR heterodimer. Reproduced with permission from Pfahl, M., Apfel, R., Bendik, I., Fanjul, A., Graupner, G., Lee, M.-O., La-Vista, N., Lu, X-P., Piedrafita, J., Ortiz, M. A., Salbert, G., and Zhang, X.-K. (1993). Nuclear retinoid receptors and their mechanism of action. Vitam. Horm., 49, 327-382.
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Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.