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11 The classifications are for age >18 years. The data are obtained from the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure.

11 The classifications are for age >18 years. The data are obtained from the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure.

modulated voltage-gated Ca2+ channel. The dominant agonist is angiotensin II, but under appropriate physiological circumstances the other agonists are also effective. Within seconds of exposure to angiotensin II, IP3, diacylglycerol (DAG), and intracellular Ca2+ concentrations all increase, followed shortly thereafter by an elevated biosynthesis of aldosterone; the details are summarized in Figure 15-8.

D. Aldosterone Actions in Renal Tubular Reabsorption

In humans, the principal biologically active mineral-ocorticoids are aldosterone, Cortisol, and, to some limited extent, deoxycorticosterone; their structures are given in Figure 2-20. The mineralocorticoids mediate

TABLE 15-5 Factors Regulating Renin Release

Inhibitory factors

Stimulatory factors

Increased renal arterial

Decreased renal arterial pressure

pressure

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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