Ho H

cooh

cooh

chconhch2cooh i nhco(ch2) chcooh 2 i nh2

cooh I Arachidonic Acid I

(5-Hydroperoxyeicosatetraenoic Acid)

cooh

(5-Hydroperoxyeicosatetraenoic Acid)

LTA4

LTA4

cooh h oh

LTB4

cooh h oh

LTB4

I chconhch2cooh

LIC4 I I

I chconhch2cooh

LIC4 I I

nhco(ch2);Ƨhcooh nh2

cooh

cooh chconhch2cooh nh2

FIGURE 16-11 Biosynthesis of LT. Subscripts are numbers of double bonds.

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