IPs subunits are not so clearly defined; they likely participate in transferring the signal transduction from the occupied receptor to the Gas and Gai subunits. There are also comparable forms of Gs that activate the phosphodiesterase and membrane channels. Table 1-7 summarizes the signal transduction activities of G proteins.

Figure 1-35 presents a model of how GTP as an activating ligand and the intrinsic GTPase enzymatic activity of the as or «¡-subunits are able to function as


Ch) g protein Receptor / Enzyme Extracellular side

Cell membrane

Intracellular side

ATP cAMP (second messenger)

Inactive protein kinase

Was this article helpful?

0 0
Cure Tennis Elbow Without Surgery

Cure Tennis Elbow Without Surgery

Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.

Get My Free Ebook

Post a comment