Apw

Endothelial cell

Intercellular /p. cement

Arteriole

Smooth muscles

Intercellular /p. cement

Arteriole

Smooth muscles

Thoroughfare Channel Biology

Precapillary sphincters

Arterial capillary

Thoroughfare channel

Venous capillary

Enlargement of true capillary

Enlargement of true capillary

Venule

FIGURE 15-6—Continued

Precapillary sphincters

Arterial capillary

Thoroughfare channel

Venous capillary where it acts within seconds. In both locations, the biological response generated by angiotensin II is mediated as a consequence of its binding to high-affinity membrane receptors; these receptors have been cloned and found to have a seven transmembrane domain that is linked to a G protein (see Chapter 1). The immediate postangiotensin II receptor-binding signal transduction events include the elevation of both IP3 and intracellular Ca2+ concentrations.

1. Aldosterone Biosynthesis

The site of production of the mineralocorticoid aldosterone is the adrenal zona glomerulosa cell, which employs a variety of signal transduction mechanisms that include receptors for angiotensin II, ACTH, dopamine, and atrial natriuretic peptide as well as a K+-

TABLE 15-4 Classification of Blood Pressure Levels

Classification"

Systolic (mm Hg)

Diastolic (mm Hg)

Normal

<130

<85

High normal

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Cure Tennis Elbow Without Surgery

Cure Tennis Elbow Without Surgery

Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.

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