In all reported studies investigating the effects of GH treatment on body composition, an increase was recorded in average LBM, varying from 2-5.5 kg after six months GH replacement (11-16,20-24). Similar findings have been reported from studies in patients with both adult-onset (AO) and childhood-onset (CO) GH-deficiency (25).
In these studies the changes in LBM were associated with reductions in fat mass of approximately 4-6 kg (11-16,20-24). Similarly this reduction occurs equally in both CO and AO GH-deficiency (25). Anthropometric measurements indicate that the most important change occurs in the abdominal region (10), corresponding to reduced visceral fat mass (16,20).
GH has a potent anti-natiuretic effect, most likely mediated through direct effects of GH and/or IGF-1 on renal tubular sodium absorption, in addition to stimulatory effects on the renin-angiotensin system (26). GH replacement results in an increase in TBW (11,18), particularly in ECW within 3-5 d (26). Plasma volume has been shown to increase after three weeks of GH replacement (17,18) and in a recent study, GH therapy resulted in a 400-mL increase in TBV after three months of treatment (18).
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If you weaken the center of any freestanding structure it becomes unstable. Eventually, everyday wear-and-tear takes its toll, causing the structure to buckle under pressure. This is exactly what happens when the core muscles are weak – it compromises your body’s ability to support the frame properly. In recent years, there has been a lot of buzz about the importance of a strong core – and there is a valid reason for this. The core is where all of the powerful movements in the body originate – so it can essentially be thought of as your “center of power.”