Neonatal glucocorticoid deficiency, 205 Neuropeptide GHD, 205 Neurosecretory dysfunction, 196, 208211
GHD, 204 Newborn period
GHD, 205 Nocturna! plasma GH profiles, 272f Non GHD short stature
GHS, 323, 324 Noninsulin dependent diabetes mellitus (NIDDM), 247 myocardial infarction, 9 pathogenic mechanisms, 248 Nonpeptide growth hormone secreta-gogues central actions, 85-92 Nutritional dwarfing GH secretion, 194
Obesity, 248, 249 GHRP-6, 32 GHS, 327
GH secretion, 199, 249, 250 GH treatment, 252—255
Obesity, fear of
GH secretion, 194 Octreotide, ¡13, 114 Oocyte expression cloning growth hormone secretagogue receptors, 70, 71 Oocyte expression systems, 71 Orally active MK-0677 animal evaluation, 57, 58 clinic, 58 discovery, 52—58 structure-activity studies, 52-57 Osteoporosis GH, 233, 243 GHD, 235-237 OTX (orthodenticlc homolog 1), 173 Ovary disease GHS, 328
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