Index
Abdominal obesity GH secretion, 249, 250 GH treatment, 252-255 Acquired growth hormone deficiency (GHD) causes, 206t Acromegalic patients, 273 Acromegaly, 250,299-301
GHRP-6, 32 Acute lymphoblastic leukemia (ALL), 196, 197 spontaneous pulsatile growth hormone secretion, 198f Adipose tissue, 248, 249 GH, 9
Adolescents. See Pediatrics Adrenocorticotropic hormone (ACTH)
GHS pattern, 318, 319 Adult-onset GHD, 306,307 GH administration, 239, 240 osteoporosis, 235, 236 Adults childhood-onset GHD
osteoporosis, 235 GH administration, 241, 242
childhood-onset GHD, 237, 238 GHD, 221-229
body composition, 223, 224 bone mineral density and bone metabolism, 224 cardiovascular system, 224, 225 exercise and strength, 225 GHS, 324
metabolism, 226, 227 quality of life, 222, 223 Syndrome X. 250-252 GHRP-2, 33-38 GHS-R ligands, 10, 11
rhGH, 46 sleep
GH secretion, 261, 262 sleep periods
GH profiles, 262f African sleeping sickness, 272 Aged. See also Adults; Eideriy GHRH treatment, 306-310 GHS, 324-326
sleep-related GH secretion, 270 siow-wave sleep, 271 f Age-related. See also Adults osteoporosis GHD, 236, 237 Agonists calcium fluctuations, 129 AIDS GH, 285-293 rhGH, 46 Alanine-scanning mutagenesis hGHR/HG interaction, 137-139 Alpha-helically-stabilized GHRH analogs, 103-105 Altitude
GH secretion, 199 Ames dwarfism
PROP-1 (prophet of pit-1), 175 191-amino acid peptide. See Pituitary
GH Amino acids benzolactam secretagogues, 52 GH secretion, 193 Animal evaluation orally active MfC-0677, 57, 58 Anorexia nervosa
GH secretion, 194 Antisensc oligonucleotides, 157 Arcuate cell identification GH secretagogue, 86—89
Arcuate nucleus activation
GH secretagogue, 86 fos-like immunorcactive, 87f GHRP-6, 86 Arginine
GH adequacy testing procedures, 182, 183
GH response, I96f Aromatic amino acid variations, 56t Atherosclerosis, 224 Atropine, 193
Autosomal dominant manner
Pit-1 deficiencies, 175 Autosomal recessive inheritance
GHAD, 178 Auxological evaluation
GH-IGF axis, 183 Awakenings
GH secretion, 268
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