Barry B Bercu md and Howard J Heinze md

Contents

Introduction

Pulsatile GH Secretion and Regulatory Mechanisms

Affecting GHRH and Somatostatin Secretion Physiologic States Affecting GH Secretion Pathophysiologic States Affecting GH Secretion Applicable to Children Hormonal Regulation of GH Secretion:

Physiology and Pathophysiology GH Deficiency and Hypopituitarism

The Clinical Utility of Spontaneous GH Secretory Profiles

Refinements on Provocative GH Secretory Testing

Ethical Issues Regarding Treatment of Short-Statured Children

Conclusions

References

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