We are indebted to our colleagues at the University of Washington, the University of Chile, and the National Institutes of Health for their collaboration and vision. We thank Suzanne Barsness, Gwen Drolet, and the dedicated staffs of the Clinical Research Cen ters at the University of Chile and the University of Washington, for their support of our studies; and Stephen Galt, Monica Kletke, and Kenneth Trimm for technical assistance. The authors' work was supported by the National Institute on Aging, the National Institute of Child Health and Human Development, the National Institute of Mental Health, the US Department of Veterans Affairs, the Beinecke Foundation, and Fondecyt grant no. 91-1020.

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