Germ cell tumors remain a biologic enigma. Despite improved knowledge of mechanisms for cure, the fundamental understanding of their biology remains incomplete. Extensive data derived from the murine teratoma model provide an intriguing window into teratoma biology although there is controversy regarding the usefulness of this information in the context of human disease. Several social, epidemio logic, and molecular factors that appear to regulate the growth and development of normal and malignant human germ cells have been identified. However, the specific linkages remain to be both biologically and clinically elucidated. It is clear that these tumors are associated with germ cell origins, predominantly young populations, cryptorchidism, infertility, a range of abnormal hormonal factors, multiple atypical nevi, and abnormalities of genetic expression. Whether there is a unifying hypothesis that explains these curiosities remains to be determined.

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100 Pregnancy Tips

100 Pregnancy Tips

Prior to planning pregnancy, you should learn more about the things involved in getting pregnant. It involves carrying a baby inside you for nine months, caring for a child for a number of years, and many more. Consider these things, so that you can properly assess if you are ready for pregnancy. Get all these very important tips about pregnancy that you need to know.

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