Cisplatin is derived from a heavy metal with known neurotoxicity and may also be associated with neu-rocognitive impairment (as has been observed with mercury and manganese).55 This topic has been poorly investigated in regard to testicular cancer. One small study compared patients with testicular cancer who were treated with chemotherapy (n = 13) to patients who were not treated with chemotherapy (n = 9) and to controls who had no history of cancer (n = 17). In this study, the group of patients who had been treated with chemotherapy performed at a lower level, according to measures of the visualmotor scanning component of attention. However, more work needs to be done in this area before firm conclusions can be made.56
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