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Figure 22-7. Photomicrograph of a seminoma, showing a conspicuous lymphocytic infiltrate amidst monotonous cells of seminoma; note the entrapped seminiferous tubule showing intratubular germ cell neoplasia-unclassified (ITGCNU). The insert shows seminoma tumor cells at a higher magnification. The patient is a 16-year-old male. These features may be compared with those of dysgerminoma and germinoma (Figures 22-11, B and 22-12, B) (original magnification x20; insert, original magnification x400).

With male adolescent patients with retroperitoneal or metastatic germ cell tumors, it is imperative that testicular ultrasonography be performed to evaluate the possibility of an occult or partially regressed testicular primary (Figure 22-8).30 Chorio-carcinoma in infancy and childhood has been reported as an extragonadal neoplasm (see below).

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10 Ways To Fight Off Cancer

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