208 women at 14—20 weeks of a singleton pregnancy from the hospital/community antenatal clinic consultation list. The sample was stratified by age, with at least 40 women in each category (under 20 years, 20-25 years, 30-35 years, 36 years and over). The response was 100% in all age groups. One woman was drawn from the selection because she expressed a communication / language difficulty. All mothers with a previous Down's syndrome pregnancy were identified from the GP's referral letter and excluded.
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