Figure 4-5. Conservation and variation in tRNA. (A) Alignments showing conserved (dots) and variable elements in the DNA sequences coding for lysine tRNA in various species; (B) alignment showing variation among the multiple copies of genes coding for serine tRNA within the human genome. Consensus (generally, the most common nucleotide at each position, even though no gene has this actual sequence) shown above each part. Bold face triplets are the mRNA-binding anticodon (this shows the redundancy of the coding system—see below).
descendant cells. In contrast, RNA is much less stable and is often enzymatically destroyed.
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