Introduction

Heartburn and Acid Reflux Cure Program

Acid Reflux Alternative Treatment

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The understanding of the pathophysiology of gastroesophageal reflux disease (GERD) has evolved in the last decade primarily by recognizing the multitude of factors that contribute to the emergence of the disorder (Fig. 1). These factors may overlap in some patients and differ in others. GERD is primarily considered a motility disorder, because dysfunction of the anti-reflux barrier is still considered as a prerequisite for the development of the disease. However, recent investigation into symptom generation in GERD disclosed the important role of altered esophageal sensation. Recent studies have demonstrated that peripheral and central factors are pivotal for the emergence of symptoms after gastroesophageal reflux had occurred; supporting the view that GERD is a sensory-mo tor disorder rather than motor disorder alone.

The primary pathophysiologic event in GERD is the movement of acid, pepsin, and other injurious substances from the stomach into the esophagus. This event also occurs as part of normal physiology, but results in GERD when symptoms or tissue damage occurs. Esophageal mucosal injury in GERD results when mucosal defensive factors are overwhelmed by refluxate, occurring secondary to compromised anti-reflux barrier, decreased effective esophageal acid clearance, abnormal mucosal defensive factors and so on.

Sensory Perception

Heightened perception of intra-esophageal acid or other reflux components

Sensory Perception

Hypotonic LES Transient LES relaxation Stress reflux Hiatal hernia

Esophageal Clearance

Abnormal peristalsis Reduced swallowed saliva

Esophageal Clearance

• Delayed gastric emptying Fig. 1. A summary of the diverse etiological factors that result in gastroesophageal reflux and symptoms

Esophageal Clearance

• Delayed gastric emptying Fig. 1. A summary of the diverse etiological factors that result in gastroesophageal reflux and symptoms

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Herbal Remedies For Acid Reflux

Herbal Remedies For Acid Reflux

Gastroesophageal reflux disease is the medical term for what we know as acid reflux. Acid reflux occurs when the stomach releases its liquid back into the esophagus, causing inflammation and damage to the esophageal lining. The regurgitated acid most often consists of a few compoundsbr acid, bile, and pepsin.

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