In 1997, Stanley B. Prusiner was awarded the Nobel Prize in Physiology or Medicine for his discovery and characterization of prions, a novel class of pathogens that cause several rare neurodegenerative diseases and that appear to replicate without any genes. Initially, Prusiner's proposal that prions were composed entirely of protein and lacked any trace of nucleic acid was met with skepticism. One of the foundations of modern biology is that all living things possess
RNA genome gag pol env
gag pol env
Viral capsid Integrase Envelope protein and reverse proteins transcriptase proteins
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