O

(A and B antibodies)

Red blood cells that do not react with the recipient antibody remain evenly dispersed. Donor blood and recipient blood are compatable.

Red blood cells that do not react with the recipient antibody remain evenly dispersed. Donor blood and recipient blood are compatable.

Blood cells that react with the recipient antibody clump together. Donor blood and recipient blood are not compatible.

4 5.5 ABO blood types and possible blood transfusions.

that successful blood transfusions are possible only between persons with certain compatible blood types ( FIGURE 5.5b).

The inheritance of alleles at the ABO locus can be illustrated by a paternity suit involving the famous movie actor Charlie Chaplin. In 1941, Chaplin met a young actress named Joan Barry, with whom he had an affair. The affair ended in February 1942 but, 20 months later, Barry gave birth to a baby girl and claimed that Chaplin was the father. Barry then sued for child support. At this time, blood typing had just come into widespread use, and Chaplin's attorneys had Chaplin, Barry, and the child blood typed. Barry had blood type A, her child had blood type B, and Chaplin had blood type O. Could Chaplin have been the father of Barry's child?

Your answer should be no. Joan Barry had blood type A, which can be produced by either genotype jaJa or Pi.

Her baby possessed blood type B, which can be produced by either genotype I8!8 or Pi. The baby could not have inherited the P allele from Barry (Barry could not carry an P allele if she were blood type A); therefore the baby must have inherited the i allele from her. Barry must have had genotype H and the baby must have had genotype A. Because the baby girl inherited her i allele from Barry, she must have inherited the P allele from her father. With blood type O, produced only by genotype ii, Chaplin could not have been the father of Barry's child. In the course of the trial to settle the paternity suit, three pathologists came to the witness stand and declared that it was genetically impossible for Chaplin to have fathered the child. Nevertheless, the jury ruled that Chaplin was the father and ordered him to pay child support and Barry's legal expenses. __

Pregnancy And Childbirth

Pregnancy And Childbirth

If Pregnancy Is Something That Frightens You, It's Time To Convert Your Fear Into Joy. Ready To Give Birth To A Child? Is The New Status Hitting Your State Of Mind? Are You Still Scared To Undergo All The Pain That Your Best Friend Underwent Just A Few Days Back? Not Convinced With The Answers Given By The Experts?

Get My Free Ebook


Post a comment