Lethal Alleles

In 1905, Lucien Cuenot reported a peculiar pattern of inheritance in mice. When he mated two yellow mice, approximately 2/3 of their offspring were yellow and 1/3 were nonyellow. When he test-crossed the yellow mice, he found that all were heterozygous; he was never able to obtain a yellow mouse that bred true. There was a great deal of

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