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^ If the amount of one product increases but amounts of other products remain the same, developmental problems often result.
I 9.9 Unbalanced gene dosage leads to developmental abnormalities.
(French for "cry of the cat") derives from the peculiar, catlike cry of infants with this syndrome. A child who is heterozygous for this deletion has a small head, widely spaced eyes, a round face, and mental retardation. Deletion of part of the short arm of chromosome 4 results in another human disorder—Wolf-Hirschhorn syndrome, which is characterized by seizures and by severe mental and growth retardation.
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