(b) To calculate the frequency of the ADHF allele after selection, we can use the table method. The frequencies of the three genotypes before selection are the Hardy-Weinberg equilibrium frequencies of p2, 2pq, and q2. We multiply each of these frequencies by the fitness of each genotype to obtain the frequencies after selection. These products are summed to obtain the mean fitness of the population (W), and the products are then divided by the mean fitness to obtain the relative genotypic frequencies after selection as shown here:

Initial genotypic frequencies:


Proportionate contribution of genotypes to population: Relative genotypic frequency after selection:


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