9.11 The Notch phenotype is produced by a chromosome deletion that includes the Notch gene.

(top, normal wing veination; bottom, wing veination produced by Notch mutation. (Spyros Artavanis-Tsakonas, Kenji Matsuno, and Mark E. Fortini).

the two chromosomes form an inversion loop ( FIGURE 9.12). The presence of an inversion loop in meiosis indicates that an inversion is present.

Individuals heterozygous for inversions also exhibit reduced recombination among genes located in the inverted region. The frequency of crossing over within the inversion is not actually diminished but, when crossing over does take place, the result is a tendency to produce gametes that are

The heterozygote has one normal chromosome.

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