Concepts

Termination takes place when the ribosome reaches a termination codon. Release factors bind to the termination codon, causing the release of the polypeptide from the last tRNA, the tRNA from the ribosome, and the mRNA from the ribosome.

The overall process of protein synthesis, including tRNA charging, initiation, elongation, and termination, is summarized in 4 Figure 15.24, and the components taking part in this process are listed in Table 15.4 (See page 00).

^ A peptide bond is formed

^ A peptide bond is formed

The tRNA that occupied the A site is now in the P site, leaving the A site open.

The unoccupied A site is now ready to receive another tRNA.

Conclusion: At the end of each cycle of elongation, the amino acid in the P site is added to the polypeptide chain and the A site is free to accept another tRNA.

The tRNA that occupied the A site is now in the P site, leaving the A site open.

The unoccupied A site is now ready to receive another tRNA.

Conclusion: At the end of each cycle of elongation, the amino acid in the P site is added to the polypeptide chain and the A site is free to accept another tRNA.

www.whfreeman.com/pierce A brief overview of translation and how it fits into the central dogma of genetics

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