Application Questions And Problems

18. A certain species has three pairs of chromosomes: an acrocentric pair, a metacentric pair, and a submetacentric pair. Draw a cell of this species as it would appear in metaphase of mitosis.

19. A biologist examines a series of cells and counts 160 cells in interphase, 20 cells in prophase, 6 cells in prometaphase,

2 cells in metaphase, 7 cells in anaphase, and 5 cells in telophase. If the complete cell cycle requires 24 hours, what is the average duration of M phase in these cells? Of metaphase?

*20. A cell in G1 of interphase has 12 chromosomes. How many chromosomes and DNA molecules will be found per cell when this original cell progresses to the following stages?

(a) G2 of interphase

(b) Metaphase I of meiosis

(c) Prophase of mitosis

(d) Anaphase I of meiosis

(e) Anaphase II of meiosis

(f) Prophase II of meiosis

(g) After cytokinesis following mitosis

(h) After cytokinesis following meiosis II

*21. All of the following cells, shown in various stages of mitosis and meiosis, come from the same rare species of plant. What is the diploid number of chromosomes in this plant? Give the names of each stage of mitosis or meiosis shown.

22. A cell has 1x amount of DNA in G1 of interphase. How much DNA (in multiples or fractions of x) will be present per cell at the following stages?

(b) Anaphase of mitosis

(c) Prophase II of meiosis

(d) After cytokinesis associated with meiosis II

23. A cell in prophase II of meiosis contains 12 chromosomes. How many chromosomes would be present in a cell from the same organism if it were in prophase of mitosis? Prophase I of meiosis?

*24. The fruit fly Drosophila melanogaster has four pairs of chromosomes, whereas the house fly Musca domestica has six pairs of chromosomes. Other things being equal, in which species would you expect to see more genetic variation among the progeny of a cross? Explain your answer.

*25. A cell has two pairs of submetacentric chromosomes, which we will call chromosomes Ia, Ib, IIa, and IIb (chromosomes Ia and Ib are homologs, and chromosomes IIa and IIb are homologs). Allele M is located on the long arm of chromosome Ia, and allele m is located at the same position on chromosome Ib. Allele P is located on the short arm of chromosome Ia, and allele p is located at the same position on chromosome Ib. Allele R is located on chromosome IIa and allele r is located at the same position on chromosome

IIb.

(a) Draw these chromosomes, labeling genes M, m, P, p, R, and r, as they might appear in metaphase I of meiosis. Assume that there is no crossing over.

(b) Considering the random separation of chromosomes in anaphase I, draw the chromosomes (with labeled genes) present in all possible types of gametes that might result from this cell going through meiosis. Assume that there is no crossing over.

26. A horse has 64 chromosomes and a donkey has 62

chromosomes. A cross between a female horse and a male donkey produces a mule, which is usually sterile. How many chromosomes does a mule have? Can you think of any reasons for the fact that most mules are sterile?

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