M A R C B L

Natural Insomnia Program

Natural Insomnia Cure and Treatment

Get Instant Access

Figure 15 Schematic illustration of melanophore activation by GPCRs. Melanophores are transfected with a plasmid vector containing cDNA encoding GPCR. Activation of Gi-coupled GPCR in melanophores inhibits adenyl cyclase and consequently phosphorylation, resulting in aggregation of melanosomes. Activation of Gs- or Gq-coupled GPCRs in melanophores activate adenyl cyclase and activate either PKA or PKC, increasing phos-phorylation, which results in dispersion of melanosomes. Melanophores can be brought to the aggregated state by activating the endogenous melatonin receptor with melatonin or can be brought into the dispersed state by exposing them to light.

Figure 15 Schematic illustration of melanophore activation by GPCRs. Melanophores are transfected with a plasmid vector containing cDNA encoding GPCR. Activation of Gi-coupled GPCR in melanophores inhibits adenyl cyclase and consequently phosphorylation, resulting in aggregation of melanosomes. Activation of Gs- or Gq-coupled GPCRs in melanophores activate adenyl cyclase and activate either PKA or PKC, increasing phos-phorylation, which results in dispersion of melanosomes. Melanophores can be brought to the aggregated state by activating the endogenous melatonin receptor with melatonin or can be brought into the dispersed state by exposing them to light.

Was this article helpful?

0 0
Natural Cures For Insomnia

Natural Cures For Insomnia

How Would You Love To Finally Get A Decent Night's Sleep? Do you toss and turn all night long without getting much of a wink of sleep? Are you tired of counting sheep for hours without falling asleep? Wouldn't you love to be able to fall asleep simply, easily and naturally, without pills, potions or harmful medicine?

Get My Free Ebook


Post a comment