1. In section 5.1 it is stated that edge detection approaches to FMD computerized analysis are more dependent on several error sources of ultrasound that registration based approaches. Can you explain why?

2. The motion model of section assumes that there is in-plane motion only. Can you comment on this?

3. The Kalmanfilter is causal, which means that its output value is a function of only the inputs that came earlier in time (could also be only later). Comment on the use of non causal tracking strategies like, for instance, noncausal Wiener filtering.

5. Why do we need to measure the nitroglycerine-mediated dilation (NMD) phase if clinical indexes are only related to the FMD phase?

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