Application to Analysis of fMRI Data

Functional MRI is a powerful modality for determining neural correlates of cognitive processes. It can be used to monitor changes of physiological parameters such as regional cerebral blood flow, regional cerebral blood volume, and blood oxygenation during cognitive tasks [126]. To extract functional information and detect activated regions using fMRI, the most widely adopted procedures are generally based on statistics theory and are paradigm dependent [65,127,128]. Cluster analysis has recently been applied to the fMRI discipline [129-131]. It is anticipated that cluster analysis will have great impact on analysis of fMRI signals for the detection of functional activation sites during cognitive tasks.

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