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Due diligence has been taken by the publishers, editors, and authors of this book to assure the accuracy of the information published and to describe generally accepted practices. The contributors herein have carefully checked to ensure that the drug selections and dosages set forth in this text are accurate and in accord with the standards accepted at the time of publication. Notwithstanding, as new research, changes in government regulations, and knowledge from clinical experience relating to drug therapy and drug reactions constantly occurs, the reader is advised to check the product information provided by the manufacturer of each drug for any change in dosages or for additional warnings and contraindications. This is of utmost importance when the recommended drug herein is a new or infrequently used drug. It is the responsibility of the treating physician to determine dosages and treatment strategies for individual patients. Further it is the responsibility of the health care provider to ascertain the Food and Drug Administration status of each drug or device used in their clinical practice. The publisher, editors, and authors are not responsible for errors or omissions or for any consequences from the application of the information presented in this book and make no warranty, express or implied, with respect to the contents in this publication.

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Printed in the United States of America. 10 9 8 7 6 5 4 3 2 1 E-ISBN 1-59259-747-5

Library of Congress Cataloging-in-Publication Data

Hematopoietic growth factors in oncology basic science and clinical therapeutics / edited by George Morstyn, MaryAnn Foote, Graham J. Lieschke.

p. ; cm. -- (Cancer drug discovery and development) Includes bibliographical references and index. ISBN 1-58829-302-5 (alk. paper)

1. Hematopoietic growth factors--Therapeutic use. 2. Hematopoietic growth factors--Mechanism of action. 3. Cancer-Chemotherapy.

[DNLM: 1. Hematopoietic Cell Growth Factors--therapeutic use. 2. Hematopoietic Cell Growth Factors--pharmacology. 3. Neoplasms--therapy. WH 140 H487383 2004] I. Morstyn, George, 1950- II. Foote, MaryAnn. III. Lieschke, Graham J. IV. Series. RC271.H43H45 2004 616.99'4061--dc22


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