Transfusion-associated HIV infection was first reported in late 1982 and early 1983. HIV antibody testing was implemented in March 1985, and over the next 5 years, only about five cases of transfusion-associated HIV infection were reported annually. In the year before testing started, 714 cases were reported (7). In late 1995, blood banks began testing donors for p24 antigen to further decrease the risk of transfusion-transmitted HIV disease. In 1999, nucleic acid testing was introduced to close the window of infectivity (from infection to detection), lowering the estimated risk for HIV transmission by blood to approx 1 in 2,000,000 units (8).
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