Degenerative Brain Disease

a Dementia of the Alzheimer type b Pick disease a Dementia of the Alzheimer type b Pick disease

Binswanger Radiology

c Binswanger disease d Normal-pressure hydrocephalus c Binswanger disease d Normal-pressure hydrocephalus

Binswanger Disease Radiology

Fig. 11.42a Inner and outer CSF spaces are much to wide for the age of this patient (65) and indicate generalized atrophy of the brain as seen in Alzheimer disease. b In Pick disease, parenchymal atrophy is limited to the frontal lobe. c Inner and outer CSF spaces are wide and the periventricular parenchyma is lower than usual in density. A small lacunar infarct is seen in the left basal ganglia (arrow). This is a patient with subcortical arteriosclerotic encephalo-pathy (SAE or Binswanger encephalopathy). d Anterior and temporal horns of the lateral ventricles as well as the third and fourth ventricle are dilated; the outer CSF spaces are of normal caliber. Scattered periventricular hypodensities (black arrows) suggest increased ventricular pressure. There is also evidence of prior infarction in the left external capsule (white arrows). (By the way: Where is the internal capsule?)

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