A. The upper limb bud site lies opposite somites C4, C5, C6, C7, C8, Tl, and T2. During week 5, mesoderm from these somites (myotomes) migrates into the limb bud and forms a posterior condensation and an anterior condensation.

B, The mesoderm of these condensations differentiates into myoblasts. The condensations then split into anatomically recognizable muscles of the upper limb; little is known about this process.

1. The posterior condensation, in general, gives rise to the extensor and supinator musculature.

2. The anterior condensation, in general, gives rise to the flexor and pronator musculature.

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