A. The dorsal column-medial lemniscus pathway mediates tactile discrimination, vibration sensation, form recognition, and joint and muscle sensation (proprioception).
B. The lateral spinothalamic pathway mediates pain and temperature sensation.
C. The lateral corticospinal tract mediates voluntary skilled motor activity.
D. The dorsal and ventral spinocerebellar tracts transmit information about proprioceptive and muscle reflex activity from the spinal cord to the cerebellum.
E. The hypothalamospinal tract influences preganglionic sympathetic neurons of the intermediolateral cell column and preganglionic parasympathetic neurons of the sacral parasympathetic nucleus. Interruption of this tract above Tl results in Horner syndrome.
VI. CLINICAL CONSIDERATIONS A. Lesions of the spinal cord
a. These lesions are classified as lower motor neuron lesions (LMN).
b. Clinical findings are those characteristic of LMN lesions: flaccid paralysis, are-flexia, atrophy, fasciculations and fibrillations, and an absent Babinski sign.
2. Amyotrophic lateral sclerosis (Lou Gehrig disease) is caused by damage to alpha motor neurons within the ventral gray horn and the lateral corticospinal tract.
a. This lesion is classified as an LMN and upper motor neuron (UMN) lesion.
b. Clinical findings are those characteristic of LMN (see VI A 1 b) and UMN lesions: spastic paralysis or paresis, no atrophy, hyperreflexia, no fasciculations or fibrillations, and a positive Babinski sign.
Was this article helpful?
If Pregnancy Is Something That Frightens You, It's Time To Convert Your Fear Into Joy. Ready To Give Birth To A Child? Is The New Status Hitting Your State Of Mind? Are You Still Scared To Undergo All The Pain That Your Best Friend Underwent Just A Few Days Back? Not Convinced With The Answers Given By The Experts?