Extent Of Local Tumour Spread

Border: pushing/infiltrative.

Lymphocytic reaction: prominent/sparse.

Limited to the appendix, into mesoappendix, appendiceal base and caecum.

As in colorectal carcinoma, prognosis relates to Dukes' stage:

A tumour confined to the appendix wall, nodes negative B tumour through the appendix wall, nodes negative C tumour in regional lymph nodes irrespective of the depth of wall invasion.

In the 6th edition TNM classification appendix is an anatomical subsite of colorectum and it applies only to carcinoma.

pTis carcinoma in situ: intraepithelial (within basement membrane) or invasion of the lamina propria (intramucosal) with no extension through muscularis mucosae into submucosa pT1 tumour invades submucosa pT2 tumour invades muscularis propria pT3 tumour invades beyond muscularis propria into subserosa or mesoappendix pT4 tumour invades the serosal surface or adjacent organs and/or perforation of visceral peritoneum.

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