Well/moderate/poor/undifferentiated, or Grade 1/2/3/4. Varies according to lesion type, e.g. keratinizing squamous carcinoma is well to moderately differentiated, non-keratinizing large cell moderate and non-keratinizing small cell poorly differentiated. About 60% are moderately differentiated. Tumour grade does not reliably predict prognosis and is only broadly indicative. However, grade 1 (small amount (<10%) of solid growth with mild nuclear atypia) has a better prognosis than grade 3 (solid pattern (>50%) with severe nuclear atypia) adeno-carcinoma. Undifferentiated carcinomas show no squamous or glandular differentiation (grade 4).
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Complete Guide to Preventing Skin Cancer. We all know enough to fear the name, just as we do the words tumor and malignant. But apart from that, most of us know very little at all about cancer, especially skin cancer in itself. If I were to ask you to tell me about skin cancer right now, what would you say? Apart from the fact that its a cancer on the skin, that is.