Manmeet Singh Ahluwalia and David M Peereboom

The role of systemic chemotherapy in high-grade gliomas (HGG) continues to evolve. The use of chemotherapy for central nervous system (CNS) malignancies poses specific challenges related to drug delivery and interactions with anticonvulsants. Chemotherapy has become standard in the adjuvant therapy of HGG. For patients with chemotherapy-sensitive subgroups of pure and mixed anaplastic oligodendrogliomas, chemotherapy represents the preferred initial therapy. Chemotherapy is often used for...

Radiation Oncology Nurse

Radiation therapy provides an important role in the management of HGG. Nursing care provided by the radiation oncology nurse begins at the initial consult visit and continues into the early post-radiation phase. Patients and families must be educated regarding treatment schedules and expected effects and side effects. Options available to patients include conventional regional radiation, whole brain radiation, stereotactic radiosurgery such as gamma knife or photon beam, brachytherapy, and...

Alternativecomplimentary Treatment

Alternative medicine has been defined as the use of various treatment modalities that are not usually used in traditional medicine, taught in medical schools, or covered by insurance companies. Terminology, however, is changing and these treatments are being incorporated more and more into traditional therapies and hence the term complimentary medicine is now used more frequently (Complimentary-Alternative Medicine CAM ). In 1991, the National Institutes of Health (NIH) established the office...

Preoperative Education

Preoperative education for the patient with a high-grade CNS malignancy is a unique challenge to nurses. Management of this patient population involves multiple treatment modalities and requires ongoing vigilance of a multidisciplinary team to detect and treat newly diagnosed and recurrent tumors. Multiple studies have indicated that preoperative education significantly reduces pre- and postoperative anxiety. Certainly, with the addition of a potential malignant diagnosis, and the often rapid...