Review Questions

1. What is the most common presenting symptom in individuals with chronic lymphocytic leukemia?

a. Massive spleens b. Thrombocytosis c. Increased calcium d. Enlarged lymph nodes

2. What are the peripheral cell indicators of an autoimmune hemolytic anemia in a patient with CLL?

a. nRBCs and spherocytes b. Smudge cells and normal lymphs c. Howell-Jolly bodies and siderocytes d. Lymphoblasts and prolymphocytes

3. A dumbbell-shaped nucleus with fragile, spiny projections like cytoplasm best describes:

a. Sezary cells.

b. lymphoblasts.

c. hairy cells.

d. smudge cells.

4. In contrast to most of the other leukemias, which of these conditions presents with a pancytopenia? a. CLL

5. Hypercalcemia in patients with multiple myeloma is the direct result of:

a. increased plasma cell mass.

b. crystalline inclusions in the plasma cells.

c. increased osteoclast activity.

d. hyperviscosity.

6. Plasmapheresis is a possible treatment for:

a. Waldenstrom's macroglobulinemia.

7. Patients with Waldenstrom's macroglobulinemia frequently encounter thrombotic complications due to:

a. increased platelet count.

b. increased megakaryocytes in the bone marrow.

c. increased plasma cells.

d. coating of platelets and clotting by increased IgM.

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