Chapter

Normochromic Anemias, Biochemical and Membrane Disorders, and Miscellaneous Red Cell Disorders, 97

Betty Ciesla

The Role of the Spleen in Red Cell

Membrane Disorders, 98 Hereditary Spherocytosis, 98

The Genetics and Pathophysiology of

Hereditary Spherocytosis, 98 Clinical Presentation in Hereditary

Spherocytosis, 98 Laboratory Diagnosis of Hereditary

Spherocytosis, 100 Treatment and Management of Hereditary Spherocytosis, 100 Hereditary Elliptocytosis, 100 Common Hereditary Elliptocytosis, 101 Southeast Asian Ovalocytosis, 101 Spherocytic Hereditary Elliptocytosis, 101

Hereditary Pyropoikilocytosis, 101

Hereditary Stomatocytosis and Hereditary

Xerocytosis, 102 Glucose-6-Phosphate Dehydrogenase

Deficiency, 102 The Genetics of Glucose-6-Phosphate

Dehydrogenase Deficiency, 102 Clinical Manifestations of Glucose-6-Phosphate Dehydrogenase Deficiency, 103

Diagnosis of Glucose-6-Phosphate Dehydrogenase Deficiency, 105 Pyruvate Kinase Deficiency, 105 Miscellaneous Red Cell Disorders, 105

Aplastic Anemia, 105 Fanconi's Anemia, 105 Diamond-Blackfan Anemia, 106 Paroxysmal Nocturnal Hemoglobinuria, 106

Cold Agglutinin Syndrome, 107 Paroxysmal Cold Hemoglobinuria, 108

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