Tissue Fluid and Lymph page 654

1. Tissue fluid formation a. Tissue fluid originates from blood plasma and includes water and dissolved substances that have passed through the capillary wall.

b. It generally lacks large proteins, but some smaller proteins leak into interstitial spaces.

c. As the protein concentration of tissue fluid increases, colloid osmotic pressure increases.

2. Lymph formation a. Increasing pressure within interstitial spaces forces some tissue fluid into lymphatic capillaries, and this fluid becomes lymph.

b. Lymph formation prevents accumulation of excess tissue fluid (edema).

3. Lymph function a. Lymph returns the smaller protein molecules and fluid to the bloodstream.

b. It transports foreign particles to the lymph nodes.

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