J

Factor X

Activates

Factor V

Factor X

Activates

Activates

Factor X

Activates

pIateIet phosphoIipids

Factor V

Prothrombin activator

Prothrombin (Factor II)

Converts

Fibrinogen (Factor I)

Figure 14.19

Schematic of blood-clotting mechanisms.

Thrombin (Factor IIa)

Converts

Fibrin

Stabilizes

Factor XIII

Fibrin cIot

Abnormal clot formations are often associated with conditions that change the endothelial linings of vessels. For example, in atherosclerosis, accumulations of fatty deposits change arterial linings, sometimes initiating inappropriate clotting. This is the most common cause of thrombosis in medium-sized arteries (fig. 14.20).

Coagulation may also occur in blood that is flowing too slowly. The concentration of clot-promoting substances may increase to a critical level instead of being carried away by more rapidly moving blood, and a clot may form. This event is the usual cause of thrombosis in

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

Get My Free Ebook


Post a comment