Lnk

25% chance 50% chance unaffected carrier 25% chance unaffected (cf allele inherited affected noncarrier from either parent)

cf

+ +

cf

cf

Mary

(b) Punnett Square (c) Bill Sue Rod Tina

Figure 24.5

Inheritance of cystic fibrosis from carrier parents illustrates autosomal recessive inheritance. (a) Each child has a 25% chance of being unaffected and not a carrier, a 50% chance of being a carrier, and a 25% chance of being affected. Sexes are affected with equal frequency. A Punnett square (b) and a pedigree (c) are other ways of depicting this information. (Note that the pedigree illustrates the make-up of one possible family.)

Unaffected parent

Unaffected parent

For each individual conceived

50% chance unaffected

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