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Imbalance of Neurotransmitter in Brain

Alzheimer disease

Memory loss, depression, disorientation, dementia, hallucinations, death

Deficient acetylcholine

Clinical depression

Debilitating, inexplicable sadness

Deficient norepinephrine and/or serotonin


Seizures, loss of consciousness

Excess GABA leads to excess norepinephrine and dopamine

Huntington disease

Personality changes, loss of coordination, uncontrollable dancelike movements, death

Deficient GABA


Excessive sleeping

Excess serotonin


Inability to sleep

Deficient serotonin


Elation, irritability, overtalkativeness, increased movements

Excess norepinephrine

Myasthenia gravis

Progressive muscular weakness

Deficient acetylcholine receptors at neuromuscular junctions

Parkinson disease

Tremors of hands, slowed movements, muscle rigidity

Deficient dopamine


Inappropriate emotional responses, hallucinations

Deficient GABA leads to excess dopamine

Sudden infant death syndrome ("crib death")

Baby stops breathing, dies if unassisted

Excess dopamine

Tardive dyskinesia

Uncontrollable movements of facial muscles

Deficient dopamine

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