Control of Cell Division page

1. Cell division capacities vary greatly among cell types.

2. Chromosome tips that shorten with each mitosis provide a mitotic clock, usually limiting the number of divisions to 50.

3. Cell division is limited, and controlled by both internal and external factors.

4. As a cell grows, its surface area increases to a lesser degree than its volume, and eventually the area becomes inadequate for the requirements of the living material within the cell. When a cell divides the daughter cells have more favorable surface area-volume relationships.

5. Cancer is the consequence of a loss of cell cycle control.

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